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On a typical Thursday afternoon in March, nearly every seat in the waiting room of the Duke Mohs Surgery Unit is full. Patients, most of them past the age of sixty, sport white gauze bandages on eyes, noses, cheeks, or foreheads. A septuagenarian in chinos, button-down shirt, and a cardigan sweater shuffles toward the multiple-option, self-serve coffeemaker and presses the button for a cup of dark roast, while a white-haired great-grandmother blazes through a crossword puzzle. The tables are stacked with a library’s worth of current publications—from The Economist and BusinessWeek to InStyle and National Geographic. Classical music plays softly, and a light scent of lavender wafts through the room from a discreetly located aromatherapy machine.
Conversations spring up between strangers. A returning patient asks a first-timer to guess where on her face she had surgery. He can’t tell—even though a few months before her top lip was cleaved nearly in two to remove a basal cell carcinoma. Every patient here has been diagnosed with some form of skin cancer. Most patients are accompanied by a spouse or friend and will spend all day at the clinic. Referred here by personal physicians, they will have cancers removed and surgical repairs completed by Jonathan Cook, director of the Mohs clinic and of dermatological surgery at Duke.
Before and After
Mohs surgeon Jonathan Cook performed a forehead flap procedure to repair and reconstruct Jennifer Steele’s nose, a portion of which was removed to eradicate an aggressive squamous cell cancer. Here’s how Steele looked after her initial surgery, and several months post-op.
Caution: The "before" picture below contains a graphic image of pre-nasal reconstruction. Viewer discretion advised before clicking to view the "before" image..
Cook is among the most accomplished Mohs surgeons in the country. A specialized subset of dermatology surgery, Mohs is a microscopic surgical procedure that removes every last cell of cancerous tissue while minimizing harm to surrounding, healthy skin and uses precise reconstruction to minimize scarring and provide a pleasing aesthetic outcome. Developed in the late 1930s by Frederic Mohs, a surgeon at the University of Wisconsin medical school, the approach has the highest success rate of any skin-cancer protocol—for new basal cell cancers, the five-year cure rate is nearly 100 percent; for recurrent cancers, it’s about 95 percent. “I got interested in Mohs when I saw cancers just being scooped out,” says Cook, as he checks the printout of the day’s schedule to see what’s next on his docket. “Even though the tumors had been successfully treated clinically, they left devastating wounds. I was confident that it was possible to remove the cancer while performing rehabilitative and reconstructive surgery. My goal is not just to get rid of cancer, but to do it so that the casual observer can’t tell that the person has had skin cancer.”
Dressed in his daily uniform of surgical scrubs, Cook is an omnipresent force in the bustling clinic, barely standing still for more than a moment. In the course of fifteen minutes, he will enter an exam room to consult with a first-time patient, stop by the on-site pathology lab to examine a tissue sample from another patient, and head into the clinic’s operating room to slice a crescent-shaped wedge from a third patient’s ear. Twelve-hour workdays are standard. Six nurses, two pathology assistants, and three front-office staff members help Cook maintain the persistent pace of the clinic. He rarely takes more than ten minutes to eat lunch—dermatology residents who rotate through are warned in advance they’ll be challenged to keep up—and takes only one week of vacation a year.
Today, Cook will see forty-five patients and perform fourteen surgical procedures. Some of these will be fairly straightforward; others, more complex. In each instance, Cook excises the cancerous growth and an area of skin surrounding and underneath it and then analyzes the tissue sample in the lab to see whether there are any remaining cancerous cells. If there are, he removes more tissue, until the slide shows no remaining cancer cells. At that point, Cook stitches up the gaping holes and deep divots that the surgery has left behind. Like other Mohs surgeons, Cook uses the intricate architecture of the human face to hide scars in the natural folds and shadows of the skin—where the cheek and nose come together, for example, or the brow area around the eye. When the tumor removal site is large, he performs additional rounds of surgery to ensure symmetry and balance.
That was the case for Jennifer Steele, a Raleigh social worker who had an aggressive squamous cell cancer growing on the left side of her nose. Squamous cell cancers are the second-most common form of skin cancer. If left untreated, they can spread to lymph nodes and other organs; about 2,500 people die from squamous cell carcinomas in the U.S. every year.
Because Cook had to remove such a large section of Steele’s nose, he recommended that she undergo what’s called a forehead flap procedure to rebuild her proboscis using a section of her forehead. The technique, which originated in India more than 3,000 years ago when cutting off noses was a form of social punishment for thieves and adulterers, redirects a section of the patient’s forehead downward so that healthy skin and blood vessels grow into place. To help the new nose retain its shape, Cook takes a sliver of cartilage from the patient’s ear and positions it on the top perimeter of the nostril he’s repairing so that it doesn’t collapse as the nose heals. The cartilage helps the nostril maintain a rounded shape, and prevents it from puckering into an unsightly scar. As with all Mohs procedures, from the simplest nip-and-stitch to extensive reconstruction, the forehead flap is performed on an outpatient basis using a local anaesthetic.
“When Dr. Cook first explained the procedure to me,” says Steele, “I was nodding but my heart was about thirty seconds behind my head. Then it hit me—I was going to be disfigured.” In the weeks following each of what would eventually be four steps of the procedure, Steele wore large bandages on her face. Children stared at her when she went out in public. A well-meaning friend told her she could never imagine leaving the house looking like that. It was emotionally exhausting, she tells Cook. She lies on a bed in the clinic’s small operating room, where he is about to begin the penultimate stage of her nose repair.
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